BDBM364490 (R or S)-2-chloro-N-[6-(1,2- dihydroxyethyl)-2-phenyl-2H- pyrazolo[4,3-b]pyridin-3-yl]-5- pyrimidin-2-yl-4- (trifluoromethyl)benzamide, isomer A::US9862707, Example 64::US9862707, Example 65
SMILES OCC(O)c1cnc2c(NC(=O)c3cc(-c4ncccn4)c(cc3Cl)C(F)(F)F)n(nc2c1)-c1ccccc1
InChI Key InChIKey=LUHUSFQQMLZGRN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 364490
Affinity DataIC50: 29nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair