BDBM364506 3-({[2-fluoro-5-pyridin-2-yl-4- (trifluoromethyl)phenyl]carbonyl} amino)-2-phenyl-2H-indazole-6- carboxamide::US9862707, Example 81

SMILES NC(=O)c1ccc2c(NC(=O)c3cc(-c4ccccn4)c(cc3F)C(F)(F)F)n(nc2c1)-c1ccccc1

InChI Key InChIKey=VJJNXINELPSTKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364506   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM364506(3-({[2-fluoro-5-pyridin-2-yl-4- (trifluoromethyl)p...)
Affinity DataIC50:  2.90nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent