BDBM364521 2-fluoro-N-{6-[2-(methylamino)-2- oxoethyl]-2-phenyl-2H-indazol-3- yl}-5-pyrimidin-2-yl-4- (trifluoromethyl)benzamide::US9862707, Example 96

SMILES CNC(=O)Cc1ccc2c(NC(=O)c3cc(c(C)cc3F)-c3ncccn3)n(nc2c1)-c1ccccc1

InChI Key InChIKey=XUZRZKLRCQZFRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364521   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM364521(2-fluoro-N-{6-[2-(methylamino)-2- oxoethyl]-2-phen...)
Affinity DataIC50:  8.90nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent