BDBM36487 CHEMBL263630::CO23

SMILES CC(C)c1cc(Oc2c(I)cc(Cc3[nH]c(=O)[nH]c3O)cc2I)ccc1O

InChI Key InChIKey=FZAMYUBHBSJYDA-UHFFFAOYSA-N

Data  4 Kd  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 36487   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.20nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.70nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  34nMAssay Description:TRE-driven dual-luciferase reporter assay in human bone osteosarcoma epithelial (U2OS) cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  390nMAssay Description:TRE-driven dual-luciferase reporter assay in human bone osteosarcoma epithelial (U2OS) cell line.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  11nMAssay Description:TRE-driven dual-luciferase reporter assay in human uterine cervical cancer (Hela) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  58nMAssay Description:Effect on human TRbeta transactivation activity in HeLa cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.20nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.70nMAssay Description:Displacement of [125I]T3 from human TRbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  34nMAssay Description:Effect on human TRalpha transactivation activity in U2OS cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  390nMAssay Description:Effect on human TRbeta transactivation activity in U2OS cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  11nMAssay Description:Effect on human TRalpha transactivation activity in HeLa cells by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataEC50:  58nMAssay Description:TRE-driven dual-luciferase reporter assay in human uterine cervical cancer (Hela) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed