BDBM36498 DADMe-ImmA-p-ClPh
SMILES: Nc1ncnc2c(CN3CC(O)C(CSc4ccc(Cl)cc4)C3)c[nH]c12
InChI Key: InChIKey=MZZBHZOHYGEGEE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methylthioadenosine Nucleosidase (MTAN) (Neisseria meningitidis) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0210 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Helicobacter pylori) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.570 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Klebsiella pneumoniae) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Phosphorylase (MTAP) (Homo sapiens (Human)) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.0100 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12)) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 0.0000470 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Streptococcus pneumoniae) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methylthioadenosine Nucleosidase (MTAN) (Staphylococcus aureus) | BDBM36498![]() (DADMe-ImmA-p-ClPh) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 8 | n/a | n/a | n/a | 7.5 | 25 |
Albert Einstein College of Medicine | Assay Description Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP. | ACS Chem Biol 2: 725-34 (2007) Article DOI: 10.1021/cb700166z BindingDB Entry DOI: 10.7270/Q2QF8R7W | |||||||||||
More data for this Ligand-Target Pair |