BDBM365008 US10633373, Example 21::US10669265, Example 21::US9868726, Example 21::methyl 4-[({6-amino-5-[5-({[(3- methylphenyl)amino]carbonyl} amino)-1-benzothien-2- yl]pyridin-3- yl}carbonyl)amino]butanoate

SMILES COC(=O)CCCNC(=O)c1cnc(N)c(c1)-c1cc2cc(NC(=O)Nc3cccc(C)c3)ccc2s1

InChI Key InChIKey=QWTWVOKZFNBXBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 365008   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365008(US10633373, Example 21 | US10669265, Example 21 | ...)
Affinity DataIC50:  118nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365008(US10633373, Example 21 | US10669265, Example 21 | ...)
Affinity DataIC50:  118nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM365008(US10633373, Example 21 | US10669265, Example 21 | ...)
Affinity DataIC50:  118nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent