BDBM365098 4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihydro-7H-6- oxa-1,2,2a1- triazabenzo[cd]azulen-4-yl)- N-(1-methyl-1H-pyrazol-5- yl)pyridin-2-amine::US11376260, Example I-47S::US9867833, Compound I-47(R)

SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2OCC[C@@H](Cn3cc(Cl)cn3)c3nnc(c1)n23

InChI Key InChIKey=JSSMLKORDMBRCS-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 365098   

TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365098(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
Affinity DataIC50:  0.465nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365098(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent