BDBM365133 9-cyclopropyl-6-methyl- 4-(2-((1-methyl-1H- pyrazol-5- yl)amino)pyrimidin-4-yl)- 8,9-dihydro-1,2,2a1,6- tetraazabenzo[cd]azulen- 7(6H)-one::US10278975, Compound I-65 R::US11376260, Example I-65S::US9867833, Compound I-65(R)
SMILES CN1c2cc(cc3nnc([C@@H](CC1=O)C1CC1)n23)-c1ccnc(Nc2ccnn2C)n1
InChI Key InChIKey=KJDYRXGMEWBQGR-AWEZNQCLSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 365133
Affinity DataIC50: 0.660nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair