BDBM365145 6-methyl-4-(2-((1-methyl-1H- pyrazol-5- yl)amino)pyrimidin-4-yl)-9- (2,2,2-trifluoroethyl)-8,9- dihydro-1,2,2a1,6- tetraazabenzo[cd]azulen- 7(6H)-one::US10517878, Compound I-71::US10842799, I-71::US9867833, Compound I-71(S)
SMILES CN1c2cc(cc3nnc(C(CC(F)(F)F)CC1=O)n23)-c1ccnc(Nc2ccnn2C)n1
InChI Key InChIKey=YEQPDWJRPJMQQH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 365145
Affinity DataIC50: 189nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.655nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: 0.655nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair