BDBM365171 9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5- yl)amino)pyridin-4-yl)-8,9- dihydro-1,2,2a1,6- tetraazabenzo[cd]azulen- 7(6H)-one::US10278975, Compound I-87 R::US11376260, Example I-87S::US9867833, Compound I-87(R)

SMILES CC(C)[C@@H]1CC(=O)N(C)c2cc(cc3nnc1n23)-c1ccnc(Nc2ccnn2C)c1

InChI Key InChIKey=MEMCTQHLJNUYLA-INIZCTEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 365171   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365171(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)
Affinity DataIC50:  6.94nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365171(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365171(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)
Affinity DataIC50:  6.94nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent