BDBM365276 US9868720, No. 307::{2-(3,3-Difluoro-azetidin- 1-yl)-6-[1-(tetrahydro- pyran-4-ylmethyl)- pyrrolidin-3-yl]-pyrimidin- 4-yl}-(4-trifluoromethyl- pyridin-2-yl)-amine

SMILES FC(F)(F)c1ccnc(Nc2cc(nc(n2)N2CC(F)(F)C2)C2CCN(CC3CCOCC3)C2)c1

InChI Key InChIKey=GJWAYZFVQJWAPH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365276   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM365276(US9868720, No. 307 | {2-(3,3-Difluoro-azetidin- 1-...)
Affinity DataKi:  31.9nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent