BDBM365922 4-{[({2,6-dimethoxy-4- [(2-methyl-3-phenylphenyl) methoxy]phenyl}methyl)amino] methyl}azetidin-2-one::US9872852, Example 174

SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CNCC1CC(=O)N1

InChI Key InChIKey=YLXAVKAGODUILD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 365922   

TargetProgrammed cell death protein 1(Homo sapiens)TBA
LigandPNGBDBM365922(4-{[({2,6-dimethoxy-4- [(2-methyl-3-phenylphenyl) ...)
Affinity DataIC50: <50nMAssay Description:Inhibition of His-tagged PD-L1 binding to PD-1-Ig (unknown origin) preincubated with PD-L1 for 15 mins followed by PD-1-Ig addition measured after 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM365922(4-{[({2,6-dimethoxy-4- [(2-methyl-3-phenylphenyl) ...)
Affinity DataIC50:  22nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent