BDBM367205 2-oxo-6-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide::US10226452, Example 23

SMILES O=C(NCCCCc1ccccc1)n1c2ccc(cc2oc1=O)-c1ccccc1

InChI Key InChIKey=RVLZFTAIRKRWIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367205   

TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367205(2-oxo-6-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  84nMAssay Description:Inhibition of recombinant human acid ceramidase expressed in HEK293 cells using N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)-4-(2-oxochromen-7-yl)-oxybutyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367205(2-oxo-6-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  84nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent