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BDBM367261 US10226464, Compound 29

SMILES: CCCCOc1cc2oc3nc(=O)[nH]c(=O)c3cc2cc1F

InChI Key: InChIKey=CCUCJOAROYGSGY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367261   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
nf-kb gfp


(Homo sapiens (Human))
BDBM367261
PNG
(US10226464, Compound 29)
Show SMILES CCCCOc1cc2oc3nc(=O)[nH]c(=O)c3cc2cc1F
Show InChI InChI=1S/C15H13FN2O4/c1-2-3-4-21-12-7-11-8(6-10(12)16)5-9-13(19)17-15(20)18-14(9)22-11/h5-7H,2-4H2,1H3,(H,17,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5.00E+3n/an/an/an/an/an/a



ImmuneTarget, Inc.

US Patent


Assay Description
NFκB/Jurkat/GFP transcriptional reporter cell line was obtained from SBI System Biosciences. NF-κB/Jurkat/GFP Reporter cells (5105 cells)...


US Patent US10226464 (2019)

More data for this
Ligand-Target Pair
emsa


(Homo sapiens (Human))
BDBM367261
PNG
(US10226464, Compound 29)
Show SMILES CCCCOc1cc2oc3nc(=O)[nH]c(=O)c3cc2cc1F
Show InChI InChI=1S/C15H13FN2O4/c1-2-3-4-21-12-7-11-8(6-10(12)16)5-9-13(19)17-15(20)18-14(9)22-11/h5-7H,2-4H2,1H3,(H,17,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/an/an/a



ImmuneTarget, Inc.

US Patent


Assay Description
DNA binding reaction (20 μL) was carried out in 1DNA Binding Buffer (10 mM Tris, 40 mM NaCl, 1 mM EDTA, 4% glycerol) with 10 nM c-Rel protein a...


US Patent US10226464 (2019)

More data for this
Ligand-Target Pair