BDBM367266 US10226464, Compound 34

SMILES CC(C)(C)CCOc1cc2oc3nc(=O)[nH]c(=O)c3cc2cc1F

InChI Key InChIKey=MQVVNTFFPUICGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367266   

TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Immunetarget

US Patent
LigandPNGBDBM367266(US10226464, Compound 34)
Affinity DataIC50:  1.00E+4nMAssay Description:NFκB/Jurkat/GFP transcriptional reporter cell line was obtained from SBI System Biosciences. NF-κB/Jurkat/GFP™ Reporter cells (5×105 cells)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Immunetarget

US Patent
LigandPNGBDBM367266(US10226464, Compound 34)
Affinity DataIC50: <500nMAssay Description:DNA binding reaction (20 μL) was carried out in 1×DNA Binding Buffer (10 mM Tris, 40 mM NaCl, 1 mM EDTA, 4% glycerol) with 10 nM c-Rel protein a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent