BDBM367656 N-((1R,2R)-1-(3-chloro-4- cyclopropoxyphenyl)-1-hydroxy-3- (pyrrolidin-1-yl)propan-2-yl)-6-(4- fluorophenyl)isochroman-1- carboxamide::US10227312, Example 42::US10759769, Example 42

SMILES O[C@@H]([C@@H](CN1CCCC1)NC(=O)C1OCCc2cc(ccc12)-c1ccc(F)cc1)c1ccc(OC2CC2)c(Cl)c1

InChI Key InChIKey=FONUWZNCWBJXAQ-JXOLXVKMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367656   

TargetCeramide glucosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM367656(N-((1R,2R)-1-(3-chloro-4- cyclopropoxyphenyl)-1-hy...)
Affinity DataIC50:  550nMAssay Description:Protein concentration was determined using BCA assay kit. Sixty micrograms of MDCK cell lysate was incubated with various concentrations of a compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCeramide glucosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM367656(N-((1R,2R)-1-(3-chloro-4- cyclopropoxyphenyl)-1-hy...)
Affinity DataIC50:  550nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent