BDBM367856 3-(2-amino-1H- benzo[d]imidazol-4-yl)-6- (azetidin-3-ylsulfonyl)-2-(2H- tetrazol-5- yl)benzenesulfonamide::US10227331, Example 43

SMILES Nc1nc2c(cccc2[nH]1)-c1ccc(c(c1-c1nn[nH]n1)S(N)(=O)=O)S(=O)(=O)C1CNC1

InChI Key InChIKey=JNQIEVJDVWORER-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367856   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367856(3-(2-amino-1H- benzo[d]imidazol-4-yl)-6- (azetidin...)
Affinity DataIC50:  0.828nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367856(3-(2-amino-1H- benzo[d]imidazol-4-yl)-6- (azetidin...)
Affinity DataIC50:  0.258nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367856(3-(2-amino-1H- benzo[d]imidazol-4-yl)-6- (azetidin...)
Affinity DataIC50:  0.0830nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent