BDBM367901 4-(4-(2-aminoethylsulfonyl)-3-sulfamoyl-2-(2H-tetrazol-5-yl)phenyl)benzo[d]thiazole-2-carboxylic acid::US10227331, Example 88

SMILES NCCS(=O)(=O)c1ccc(-c2cccc3sc(nc23)C(O)=O)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key InChIKey=AHTXJNLBDXSMQQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367901   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367901(4-(4-(2-aminoethylsulfonyl)-3-sulfamoyl-2-(2H-tetr...)
Affinity DataIC50:  0.144nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367901(4-(4-(2-aminoethylsulfonyl)-3-sulfamoyl-2-(2H-tetr...)
Affinity DataIC50:  0.158nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367901(4-(4-(2-aminoethylsulfonyl)-3-sulfamoyl-2-(2H-tetr...)
Affinity DataIC50:  0.0520nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent