BDBM368094 6-((S)-3-amino-2-hydroxypropylsulfonyl)-3-(2-aminobenzo[d]thiazol-4-yl)-2-(2H-tetrazol-5-yl)benzenesulfonamide::US10227331, Example 281

SMILES NC[C@H](O)CS(=O)(=O)c1ccc(-c2cccc3sc(N)nc23)c(-c2nn[nH]n2)c1S(N)(=O)=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 368094   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368094(6-((S)-3-amino-2-hydroxypropylsulfonyl)-3-(2-amino...)
Affinity DataIC50:  0.126nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368094(6-((S)-3-amino-2-hydroxypropylsulfonyl)-3-(2-amino...)
Affinity DataIC50:  0.134nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM368094(6-((S)-3-amino-2-hydroxypropylsulfonyl)-3-(2-amino...)
Affinity DataIC50:  0.0560nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent