BDBM3681 2-N-methyl-8-N-phenyl-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 4c::6-(Methylamino)-4-(phenylamino)pyrimido[5,4-d]pyrimidine

SMILES CNc1ncc2ncnc(Nc3ccccc3)c2n1

InChI Key InChIKey=HSTFDYRLOHVGKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3681   

TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3681(2-N-methyl-8-N-phenyl-[1,3]diazino[5,4-d]pyrimidin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3681(2-N-methyl-8-N-phenyl-[1,3]diazino[5,4-d]pyrimidin...)
Affinity DataIC50:  13nMpH: 7.4 T: 22°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed