BDBM368553 N-(naphthalen-2-yl)-1H- pyrazolo[4,3-b]pyridin-3- amine::US10227343, Example 88

SMILES N(c1n[nH]c2cccnc12)c1ccc2ccccc2c1

InChI Key InChIKey=FAUFNAAZZSERRI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368553   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM368553(N-(naphthalen-2-yl)-1H- pyrazolo[4,3-b]pyridin-3- ...)
Affinity DataEC50:  403nMAssay Description:Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM368553(N-(naphthalen-2-yl)-1H- pyrazolo[4,3-b]pyridin-3- ...)
Affinity DataEC50:  403nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent