BDBM368817 (2R)-N-(4-dimethylaminophenyl)-2-methyl-4- [6-(4-pyridyl)-7H-pyrrolo[2,3-d]pyrimidin-4- yl]piperazine-1-carboxamide::US10227357, Compound P-0066

SMILES C[C@@H]1CN(CCN1C(=O)Nc1ccc(cc1)N(C)C)c1ncnc2[nH]c(cc12)-c1ccncc1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368817   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM368817((2R)-N-(4-dimethylaminophenyl)-2-methyl-4- [6-(4-p...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM368817((2R)-N-(4-dimethylaminophenyl)-2-methyl-4- [6-(4-p...)
Affinity DataKi:  5.50E+3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent