BindingDB PrimarySearch

BDBM36882 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-bis(oxidanyl)-2-(trifluoromethyl)chromen-4-one::3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-dihydroxy-2-(trifluoromethyl)-1-benzopyran-4-one::3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-dihydroxy-2-(trifluoromethyl)chromen-4-one::3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-dihydroxy-2-(trifluoromethyl)chromone::MLS000038402::SMR000035462::cid_5389033

SMILES: Oc1cc(O)c2c(c1)oc(c(-c1ccc3OCCOc3c1)c2=O)C(F)(F)F

InChI Key: InChIKey=WRHCXHSYKVXVMV-UHFFFAOYSA-N

Data: 4 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 36882
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM36882 (3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-bis(oxida...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	Article PCBioAssay	n/a	n/a	n/a	n/a	3.84E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) Article DOI: 10.1021/bi701954p BindingDB Entry DOI: 10.7270/Q2ZC817P
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM36882 (3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-bis(oxida...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2WQ028B
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM36882 (3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-bis(oxida...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	Article PCBioAssay	n/a	n/a	n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) Article DOI: 10.1021/cb300426u BindingDB Entry DOI: 10.7270/Q2251GJ9
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM36882 (3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-bis(oxida...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	Article PCBioAssay	n/a	n/a	n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q25X2795
					More data for this Ligand-Target Pair