BDBM368988 N-[3-fluoro-4-[7-methoxy-6-(3- morpholinopropoxy)quinazolin-4- yl]phenyl]methanesulfonamide::US10227357, Compound P-0252

SMILES COc1cc2ncnc(-c3ccc(NS(C)(=O)=O)cc3F)c2cc1OCCCN1CCOCC1

InChI Key InChIKey=PLQDXTLFMYCSLJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368988   

TargetMast/stem cell growth factor receptor Kit [D816V](Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM368988(N-[3-fluoro-4-[7-methoxy-6-(3- morpholinopropoxy)q...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM368988(N-[3-fluoro-4-[7-methoxy-6-(3- morpholinopropoxy)q...)
Affinity DataKi:  1.05E+5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent