BDBM3696 4-[(3-Methylphenyl)amino]-6-[[2-(4-morpholino)ethyl]-amino]pyrimido[5,4-d]pyrimidine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6g::8-N-(3-methylphenyl)-2-N-[2-(morpholin-4-yl)ethyl]-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine

SMILES Cc1cccc(Nc2ncnc3cnc(NCCN4CCOCC4)nc23)c1

InChI Key InChIKey=COTLDEHUICFEBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3696   

TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3696(4-[(3-Methylphenyl)amino]-6-[[2-(4-morpholino)ethy...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed
TargetEpidermal growth factor receptor(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM3696(4-[(3-Methylphenyl)amino]-6-[[2-(4-morpholino)ethy...)
Affinity DataIC50:  2.30nMpH: 7.4 T: 22°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMed