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BDBM369630 US10233152, Example 137

SMILES: O=c1[nH]c2ccc(OCCN3CCC(CC3)N[C@@H]3C[C@H]3c3ccccc3)cc2o1

InChI Key: InChIKey=PVOROURTRAYOPB-LMPOMZQGNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369630   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM369630
PNG
(US10233152, Example 137)
Show SMILES O=c1[nH]c2ccc(OCCN3CCC(CC3)N[C@@H]3C[C@H]3c3ccccc3)cc2o1
Show InChI InChI=1/C23H27N3O3/c27-23-25-20-7-6-18(14-22(20)29-23)28-13-12-26-10-8-17(9-11-26)24-21-15-19(21)16-4-2-1-3-5-16/h1-7,14,17,19,21,24H,8-13,15H2,(H,25,27)/t19-,21+/s2
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



MIRATI THERAPEUTICS, INC.

US Patent


Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...


US Patent US10233152 (2019)

More data for this
Ligand-Target Pair