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BDBM369648 US10233152, Example 155

SMILES: CCS(=O)(=O)NC(=O)CCCN1CCC(CC1)N[C@@H]1C[C@H]1c1ccccc1

InChI Key: InChIKey=HGRWVMKZZYRLIX-QINVSXPYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369648   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM369648
PNG
(US10233152, Example 155)
Show SMILES CCS(=O)(=O)NC(=O)CCCN1CCC(CC1)N[C@@H]1C[C@H]1c1ccccc1
Show InChI InChI=1/C20H31N3O3S/c1-2-27(25,26)22-20(24)9-6-12-23-13-10-17(11-14-23)21-19-15-18(19)16-7-4-3-5-8-16/h3-5,7-8,17-19,21H,2,6,9-15H2,1H3,(H,22,24)/t18-,19+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 134n/an/an/an/an/an/a



MIRATI THERAPEUTICS, INC.

US Patent


Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...


US Patent US10233152 (2019)

More data for this
Ligand-Target Pair