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BDBM369652 US10233152, Example 159

SMILES: Cc1cc(CC(O)=O)ccc1OCCN1CCC(CC1)N[C@@H]1C[C@H]1c1ccccc1

InChI Key: InChIKey=CJLWVGVMDVIXLU-VUEPYQETNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369652   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM369652
PNG
(US10233152, Example 159)
Show SMILES Cc1cc(CC(O)=O)ccc1OCCN1CCC(CC1)N[C@@H]1C[C@H]1c1ccccc1
Show InChI InChI=1/C25H32N2O3/c1-18-15-19(16-25(28)29)7-8-24(18)30-14-13-27-11-9-21(10-12-27)26-23-17-22(23)20-5-3-2-4-6-20/h2-8,15,21-23,26H,9-14,16-17H2,1H3,(H,28,29)/t22-,23+/s2
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



MIRATI THERAPEUTICS, INC.

US Patent


Assay Description
Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...


US Patent US10233152 (2019)

More data for this
Ligand-Target Pair