BDBM369945 (R)—N-(2-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-cyclobutyl-2-oxoethyl)-2-fluoro-5-(trifluoromethyl)benzamide::US10233182, Example 58

SMILES CN1C(=O)N(c2ccc3[nH]ncc3c2)C2(CCN(CC2)C(=O)[C@H](NC(=O)c2cc(ccc2F)C(F)(F)F)C2CCC2)C1=O

InChI Key

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369945   

LigandPNGBDBM369945((R)—N-(2-(1-(1H-Indazol-5-yl)-3-methyl-2,4-di...)
Affinity DataIC50: <500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent