BDBM369976 5-Ethyl-2-fluoro-N-((2R,3S)-3-methoxy-1-(3-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-yl)-1-oxobutan-2-yl)benzamide::US10233182, Example 133
SMILES CCc1ccc(F)c(c1)C(=O)N[C@H]([C@H](C)OC)C(=O)N1CCC2(CC1)N(CN(C)C2=O)c1ccccc1
InChI Key InChIKey=GOECOLXTEALSPU-YADARESESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 369976
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
X-Rx
US Patent
X-Rx
US Patent
Affinity DataIC50: <500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair