BDBM370004 (R)N-(1-(1-(4-(Cyanomethoxy)phenyl)-3-methyl-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-5-ethyl-2-fluorobenzamide::US10233182, Example 170
SMILES CCc1ccc(F)c(c1)C(=O)N[C@H](C(C)C)C(=O)N1CCC2(CC1)N(CN(C)C2=O)c1ccc(OCC#N)cc1
InChI Key InChIKey=BYUJUUYDYMRQPL-AREMUKBSSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 370004
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
X-Rx
US Patent
X-Rx
US Patent
Affinity DataIC50: <500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair