BDBM370004 (R)—N-(1-(1-(4-(Cyanomethoxy)phenyl)-3-methyl-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-5-ethyl-2-fluorobenzamide::US10233182, Example 170

SMILES CCc1ccc(F)c(c1)C(=O)N[C@H](C(C)C)C(=O)N1CCC2(CC1)N(CN(C)C2=O)c1ccc(OCC#N)cc1

InChI Key InChIKey=BYUJUUYDYMRQPL-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370004   

LigandPNGBDBM370004((R)—N-(1-(1-(4-(Cyanomethoxy)phenyl)-3-methyl...)
Affinity DataIC50: <500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent