BDBM370524 1-(4-((S)-1-hydroxy-2-((S)-5H-imidazo[5,1- a]isoindol-5-yl)ethyl)piperidin-1-yl)-2- phenylethanone::US10233190, Example 1447::US10233190, Example 1481

SMILES O[C@@H](C[C@H]1c2ccccc2-c2cncn12)C1CCN(CC1)C(=O)Cc1ccccc1

InChI Key InChIKey=YEBWNEBTTYUFMD-UPVQGACJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370524   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM370524(1-(4-((S)-1-hydroxy-2-((S)-5H-imidazo[5,1- a]isoin...)
Affinity DataIC50: <1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

US Patent
LigandPNGBDBM370524(1-(4-((S)-1-hydroxy-2-((S)-5H-imidazo[5,1- a]isoin...)
Affinity DataIC50: <1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent