BDBM370556 (1R,4r)-4-((R)-2-((R)-6-fluoro-5H-imidazo[5,1- a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol::US10233190, Example 1489

SMILES O[C@H](C[C@@H]1c2c(cccc2F)-c2cncn12)[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=YGACXVRLDHEXKY-GADXADSLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370556   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM370556((1R,4r)-4-((R)-2-((R)-6-fluoro-5H-imidazo[5,1- a]i...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM370556((1R,4r)-4-((R)-2-((R)-6-fluoro-5H-imidazo[5,1- a]i...)
Affinity DataIC50:  550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In DepthDetails US Patent