BDBM370672 US10238743, Example 47
SMILES CN1C(=N)N[C@@]2(C)[C@H](CCOc3ccc(NC4CCCC4)cc23)S1(=O)=O
InChI Key InChIKey=RWPYRLCUTYIVDS-FUHWJXTLSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 370672
Affinity DataKi: 348nMAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
Affinity DataKi: 716nMAssay Description:Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...More data for this Ligand-Target Pair