BDBM370821 2-ethoxy-N-ethyl-N-{2-[6-(1- hydroxy-1-methylethyl)pyridin-2- yl]ethyl}pyridine-3-carboxamide::US10239838, Example 6

SMILES CCOc1ncccc1C(=O)N(CC)CCc1cccc(n1)C(C)(C)O

InChI Key InChIKey=ROVSQKSCMYOCET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370821   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370821(2-ethoxy-N-ethyl-N-{2-[6-(1- hydroxy-1-methylethyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370821(2-ethoxy-N-ethyl-N-{2-[6-(1- hydroxy-1-methylethyl...)
Affinity DataIC50:  206nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent