BDBM370828 N-ethyl-4-fluoro-N-{2-[6-(1- hydroxy-1-methylethyl)pyridin-2- yl]ethyl}-2-(2H-1,2,3-triazol-2- yl)benzamide::US10239838, Example 13

SMILES CCN(CCc1cccc(n1)C(C)(C)O)C(=O)c1ccc(F)cc1-n1nccn1

InChI Key InChIKey=IGXJXPSSDRUBRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370828   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370828(N-ethyl-4-fluoro-N-{2-[6-(1- hydroxy-1-methylethyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370828(N-ethyl-4-fluoro-N-{2-[6-(1- hydroxy-1-methylethyl...)
Affinity DataIC50:  8nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent