BDBM37115 4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine::5-(3,4-diethoxyphenyl)-3-(4-pyridyl)-1,2,4-oxadiazole::5-(3,4-diethoxyphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole::MLS000063560::SMR000075132::US10544136, Compound 35::cid_976135

SMILES CCOc1ccc(cc1OCC)-c1nc(no1)-c1ccncc1

InChI Key InChIKey=MMKXHTDCKLZHIM-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 37115   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37115(4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyr...)
Affinity DataEC50:  226nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37115(4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyr...)
Affinity DataEC50:  2.77E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Networ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37115(4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyr...)
Affinity DataEC50:  661nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37115(4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyr...)
Affinity DataEC50:  207nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37115(4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyr...)
Affinity DataEC50:  3.70nMAssay Description:The method involves contacting the receptor with a suitable concentration of an inventive compound to bring about activation of the receptor. The con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37115(4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyr...)
Affinity DataEC50: >9.51E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay