BDBM371525 4-chloro-2-methyl-5-(((1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino)pyridazin-3(2H)-one::US10239861, Example 5

SMILES CN1[C@H]2CC[C@@H]1C[C@@H](C2)Nc1cnn(C)c(=O)c1Cl

InChI Key InChIKey=SQYCIYZYXUMJEO-ILWJIGKKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371525   

TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM371525(4-chloro-2-methyl-5-(((1R,3r,5S)-8-methyl-8-azabic...)
Affinity DataIC50:  480nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent