BDBM371539 4-chloro-5-(((3S,5R)-5-isobutyl-1-methylpiperidin-3-yl)amino)-2-methypyridazin-3(2H)-one and 4-chloro-5-(((3R,5S)-5-isobutyl-1-methylpiperidin-3-yl)amino)-2-methylpyridazin-3(2H)-one::US10239861, Example 19

SMILES CC(C)C[C@@H]1C[C@@H](CN(C)C1)Nc1cnn(C)c(=O)c1Cl

InChI Key InChIKey=PYCNZAAZGQDRJG-NEPJUHHUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371539   

TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM371539(4-chloro-5-(((3S,5R)-5-isobutyl-1-methylpiperidin-...)
Affinity DataIC50:  1.98E+3nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent