BDBM371551 4-chloro-2-methyl-5-((1-(oxetan-3-yl)piperidin-3-yl)amino)pyridazin-3(2H)-one::US10239861, Example 31

SMILES Cn1ncc(NC2CCCN(C2)C2COC2)c(Cl)c1=O

InChI Key InChIKey=CFRDBPXDMMANCI-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371551   

TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM371551(4-chloro-2-methyl-5-((1-(oxetan-3-yl)piperidin-3-y...)
Affinity DataIC50:  1.22E+3nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent