BDBM371553 4-chloro-2-methyl-5-((1-(pyridin-2-ylmethyl)piperidin-3-yl)amino)pyridazin-3(2H)-one::US10239861, Example 33

SMILES Cn1ncc(NC2CCCN(Cc3ccccn3)C2)c(Cl)c1=O

InChI Key InChIKey=JQFSARUOROKFGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371553   

TargetHistone acetyltransferase KAT2B(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM371553(4-chloro-2-methyl-5-((1-(pyridin-2-ylmethyl)piperi...)
Affinity DataIC50:  1.98E+3nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent