BDBM371892 US10239870, Example 114::US10239870, Example 115

SMILES Cn1c(SCCCN2CC[C@]3(CC3c3ccc(cc3)C(F)(F)F)C2)nnc1N1CCOCC1

InChI Key InChIKey=XNMSLJNWIPSTJD-BPARTEKVSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 371892   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Indivior

US Patent
LigandPNGBDBM371892(US10239870, Example 114 | US10239870, Example 115)
Affinity DataKi:  1.91nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Indivior

US Patent
LigandPNGBDBM371892(US10239870, Example 114 | US10239870, Example 115)
Affinity DataKi:  17.8nMAssay Description:[125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM371892(US10239870, Example 114 | US10239870, Example 115)
Affinity DataKi:  97.7nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were seeded into b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Indivior

US Patent
LigandPNGBDBM371892(US10239870, Example 114 | US10239870, Example 115)
Affinity DataKi:  1.62E+3nMAssay Description:CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were seeded into b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent