BDBM372058 3-(2-Chloro-5-trifluoromethyl-phenyl)-8-(1H-indazole-5-carbonyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::US10239876, Example 81::US10435407, Example 81

SMILES FC(F)(F)c1ccc(Cl)c(c1)N1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O

InChI Key InChIKey=XYSZXRGZRNKPHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372058   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM372058(3-(2-Chloro-5-trifluoromethyl-phenyl)-8-(1H-indazo...)
Affinity DataIC50:  1.85E+3nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM372058(3-(2-Chloro-5-trifluoromethyl-phenyl)-8-(1H-indazo...)
Affinity DataIC50:  1.85E+3nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent