BDBM372071 N-(2,2-Difluoroethyl)-2-[4-oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-1,3,8-triazaspiro[4.5]decan-3-yl]acetamide::US10239876, Example 94::US10435407, Example 94

SMILES FC(F)CNC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O

InChI Key InChIKey=QHJQBVFNRUEDHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372071   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM372071(N-(2,2-Difluoroethyl)-2-[4-oxo-1-phenyl-8-(1H-pyra...)
Affinity DataIC50:  65.4nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM372071(N-(2,2-Difluoroethyl)-2-[4-oxo-1-phenyl-8-(1H-pyra...)
Affinity DataIC50:  65.4nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent