BDBM372118 2-[4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-1,3,8-triazaspiro[4.5]decan-3-yl]-N-[1-(2,2,2-trifluoroethyl)pyrazol-3-yl]acetamide::US10239876, Example 141::US10435407, Example 141

SMILES FC(F)(F)Cn1ccc(NC(=O)CN2CN(c3ccccc3)C3(CCN(CC3)C(=O)c3cnc4[nH]ncc4c3)C2=O)n1

InChI Key InChIKey=QGKXLHRKUNKGPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372118   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM372118(2-[4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-...)
Affinity DataIC50:  208nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM372118(2-[4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-...)
Affinity DataIC50:  208nMAssay Description:This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent