BDBM372148 N,6-diphenyl-5H- pyrrolo[3,2- d]pyrimidin-2-amine::US10239881, Example A1::US10875863, Example A1

SMILES N(c1ccccc1)c1ncc2[nH]c(cc2n1)-c1ccccc1

InChI Key InChIKey=YHCGTIVCLOQBAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372148   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372148(N,6-diphenyl-5H- pyrrolo[3,2- d]pyrimidin-2-amine ...)
Affinity DataIC50: >500nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372148(N,6-diphenyl-5H- pyrrolo[3,2- d]pyrimidin-2-amine ...)
Affinity DataIC50: >500nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent