BDBM372163 2-(4-(3-((6-(2- chlorophenyl)-5H- pyrrolo[3,2- d]pyrimidin-2- yl)amino)phenyl) piperazin-1-yl) ethanol::US10239881, Example A16::US10875863, Example A16

SMILES OCCN1CCN(CC1)c1cccc(Nc2ncc3[nH]c(cc3n2)-c2ccccc2Cl)c1

InChI Key InChIKey=DFYXCLCXXSZGCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372163   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372163(2-(4-(3-((6-(2- chlorophenyl)-5H- pyrrolo[3,2- d]p...)
Affinity DataIC50: <100nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372163(2-(4-(3-((6-(2- chlorophenyl)-5H- pyrrolo[3,2- d]p...)
Affinity DataIC50: <100nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent