BDBM372171 N-((tetrahydro- 2H-pyran-4-yl) methyl)-6- (o-tolyl)-5H- pyrrolo[3,2- d]pyrimidin-2- amine::US10239881, Example A24::US10875863, Example A24

SMILES Cc1ccccc1-c1cc2nc(NCC3CCOCC3)ncc2[nH]1

InChI Key InChIKey=DILJAAGIGNJODE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372171   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372171(N-((tetrahydro- 2H-pyran-4-yl) methyl)-6- (o-tolyl...)
Affinity DataIC50:  300nMAssay Description:Active RIPK2 was purchased from Life Technologies as His-tagged of catalytic domain (amin acids 1-299) of human RIPK2 kinase expressed in insect cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Health Network

US Patent
LigandPNGBDBM372171(N-((tetrahydro- 2H-pyran-4-yl) methyl)-6- (o-tolyl...)
Affinity DataIC50:  300nMAssay Description:RIPK2 activity was measured using an indirect ELISA detection system. His—RIPK2 (0.6 nM) was incubated in the presence of 6 μM ATP (Sigma cat # ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent