BDBM372342 Preparation of (R)-1-(fluoromethyl)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b, 8,8,11a-pentamethyl-3a-((2-(4-(methylsulfonyl)piperidin-1-yl)ethyl)amino)-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11 b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)cyclohex-3-enecarboxylic acid::US10245275, Example 1b

SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCC(CC1)S(C)(=O)=O

InChI Key InChIKey=GXCQXEGPZPHUSE-NXHRSJIFSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372342   

TargetGag-Pol polyprotein [A364V](Human immunodeficiency virus type 1 group M subtyp...)
Viiv Healthcare UK (No. 4)

US Patent
LigandPNGBDBM372342(Preparation of (R)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Affinity DataEC50:  176nMAssay Description:MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Viiv Healthcare UK (No. 4)

US Patent
LigandPNGBDBM372342(Preparation of (R)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Affinity DataEC50:  1.93nMAssay Description:MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent