BDBM372395 Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-(isopentylamino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)cyclohex-3-enecarboxylic acid::US10245275, Example 2-7

SMILES CC(C)CCN[C@]12CC[C@H]([C@@H]1[C@H]1CC[C@@H]3[C@@]4(C)CC=C(C5=CC[C@@](CF)(CC5)C(O)=O)C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)CC2)C(C)=C

InChI Key InChIKey=BMIFKPDPEPSHKP-QRLWGUERSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 372395   

TargetGag-Pol polyprotein [A364V](Human immunodeficiency virus type 1 group M subtyp...)
Viiv Healthcare UK (No. 4)

US Patent
LigandPNGBDBM372395(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Affinity DataEC50:  3.00E+3nMAssay Description:MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Viiv Healthcare UK (No. 4)

US Patent
LigandPNGBDBM372395(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Affinity DataEC50:  116nMAssay Description:MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent